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Had COVID? You’ll probably make antibodies for a lifetime

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2021-05-28 13:30:05

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A bone marrow plasma cell (artificially coloured). Such cells, which produce antibodies, linger for months in the bodies of people who have recovered from COVID-19. Credit: Dr Gopal Murti/Science Photo Library

Many people who have been infected with SARS-CoV-2 will probably make antibodies against the virus for most of their lives. So suggest researchers who have identified long-lived antibody-producing cells in the bone marrow of people who have recovered from COVID-191.

The study provides evidence that immunity triggered by SARS-CoV-2 infection will be extraordinarily long-lasting. Adding to the good news, “the implications are that vaccines will have the same durable effect,” says Menno van Zelm, an immunologist at Monash University in Melbourne, Australia.

Antibodies — proteins that can recognize and help to inactivate viral particles — are a key immune defence. After a new infection, short-lived cells called plasmablasts are an early source of antibodies.

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