Low-carbohydrate diets and all-cause and cause-specific mortality: Two cohort Studies
Rob van Dam: Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore 117597
To examine the association of low-carbohydrate diets with mortality during 26 years of follow-up in women and 20 years in men.
A prospective cohort study of women and men, followed from 1980 (women) or 1986 (men) until 2006. Low-carbohydrate diets, either animal-based (emphasizing animal sources of fat and protein), or vegetable-based (emphasizing vegetable sources of fat and protein) were computed from multiple validated food frequency questionnaire assessed during follow-up.
85,168 women (aged 34-59 years at baseline) and 44,548 men (aged 40-75 years at baseline) without heart disease, cancer, or diabetes.
Investigator documented 12,555 deaths (2,458 cardiovascular, 5,780 cancer) in women and 8,678 deaths (2,746 cardiovascular, 2,960 cancer) in men.
