Gut Microbiome Disruption Linked to Aggression
Summary: Disruptions in the gut microbiome, especially due to early-life antibiotic use, lead to increased aggression in mice. Researchers transplanted microbiomes from infants exposed to antibiotics into mice and found a clear connection between altered gut bacteria and aggressive behavior.
The study also identified changes in neurotransmitter levels and gene expression in brain regions associated with aggression. These findings highlight the role of the gut-brain axis in shaping behavior and could lead to future interventions for social behavior issues.
A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior in mice.
Published in the journal Brain, Behavior, and Immunity, the research explores how disruptions in the microbiome, particularly due to antibiotic use in early life, can lead to increased aggression.
