Why Womens have Higher Rate of Alzheimer's
Loss of estrogen related to menopause may explain why women are much more likely than men to develop Alzheimer disease (AD), new research suggests. In a study of more than 120 participants, menopausal status was the main factor contributing to higher beta amyloid (Aβ) levels, lower glucose metabolism, and lower gray matter volume (GMV) and…
Loss of estrogen related to menopause may explain why women are much more likely than men to develop Alzheimer disease (AD), new research suggests.
In a study of more than 120 participants, menopausal status was the main factor contributing to higher beta amyloid (Aβ) levels, lower glucose metabolism, and lower gray matter volume (GMV) and white matter volume (WMV) in women.
“Our findings suggest that hormonal factors may predict who will have changes in the brain,” study author Lisa Mosconi, PhD, associate professor of neuroscience in neurology, director of the Women’s Brain Initiative, and associate director of the Alzheimer’s Prevention Clinic, Weill Cornell Medicine, New York City, said in a press release.
“The results show changes in brain imaging features, or biomarkers in the brain, suggesting menopausal status may be the best predictor of Alzheimer’s-related brain changes in women,” Mosconi added.
