Charles Darwin’s work on heredity was partly driven by tragic losses in his own family. Darwin had married his first cousin, Emma, and “wondered if his close genetic relation to his wife had had an ill impact on his children’s health, three (of 10) of whom died before the age of 11,” Katherine Harmon writes at Scientific American. (His suspicions, researchers surmise, may have been correct.) He was so concerned about the issue that, in 1870, he pressured the government to include questions about inbreeding on the census (they refused).
Darwin’s children would serve as subjects of scientific observation. His notebooks, says Alison Pearn of the Darwin Correspondence Project at Cambridge University Library, show a curious father “prodding and poking his young infant,” Charles Erasmus, his first child, “like he’s another ape.” Comparisons of his children’s development with that of orangutans helped him refine ideas in On the Origin of Species, which he completed as he raised his family at their house in rural Kent, and inspired later ideas in Descent of Man.
But as they grew, the Darwin children became far more than scientific curiosities. They became their father’s assistants and apprentices. “It’s really an enviable family life,” Pearn tells the BBC. “The science was everywhere. Darwin just used anything that came to hand, all the way from his children right through to anything in his household, the plants in the kitchen garden.” Steeped in scientific investigation from birth, it’s little wonder so many of the Darwins became accomplished scientists themselves.