Trailblazing medical researcher Dr. Jonathan Sackner-Bernstein offers a new theory about the causes (and potential treatments) for Parkinson's, which could upend the prevailing treatments for the disease.
HASTINGS-ON-HUDSON, N.Y. , June 8, 2021 /PRNewswire/ -- This week The Journal of Parkinson's Disease published a peer-reviewed scientific study by Dr. Jonathan Sackner-Bernstein positing that the standard way to treat Parkinson's might be precisely the opposite of what would be the most effective. The data in this new study show that instead of focusing on increasing brain dopamine in Parkinson's patients, a more scientifically rational approach would be to reduce the amount of dopamine within the cells in the brain that control movement.
Data from the study of human brain tissue includes many different types of cells and the materials that connect and bathe them. Sackner-Bernstein's analysis confirmed the marked reduction in tissue dopamine, by 82% in the caudate and 96% in the putamen – the two areas of the human brain most affected by Parkinson's.