Scientists develop technique to analyze RNA structures in ultra-high definition
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Scientists at the University of Nottingham have developed a technique to analyze the atomic-level structure of RNA molecules with exceptional precision and speed, and are the first in the world to use the method to examine structural changes in RNA when a cell gets infected with HIV.
The findings, which are published in Nature Communications, could have far-reaching implications for the treatment of various diseases where RNA plays a critical role and for development of therapeutics such as mRNA vaccines.
RNA, a close cousin of DNA, plays a critical role in various biological processes, from protein synthesis to gene regulation. However, unlike the DNA's well-known double-helix structure, RNA folds into complex shapes that are incredibly difficult to analyze using traditional techniques.
