Scientists create a cell that precludes malignant growth

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Cell therapies could help in the treatment of hereditary diseases, myocardial infarction and hundreds of other diseases. For many blood diseases, new cells can already be transplanted into human patients, and diabetes has also been treated by transplanting cells obtained through organ donation or, more recently, β-cells modified from the patient's own stem cells.

A risk associated with gene-edited cells is unintentional DNA mutations, including those that predispose patients to cancer. Moreover, the difference in tissue types makes it impossible to transfer cells simply from one person to another.

Cells that suit anyone, or immunologically invisible cells, as it were, have been created, but they too are associated with an increased risk of cancer. Over a decade ago, Docent and Clinical Geneticist Kirmo Wartiovaara's research group set out to develop cells where these problems could be avoided. Now, the group has succeeded in producing cells which cannot proliferate unaided and which cannot therefore turn into malignant cells.

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