Integrated platform implements brain-like layered neuronal structures using 3D printing technology
edited by Lisa Lock, reviewed by Andrew Zinin
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Existing three-dimensional (3D) neuronal culture technology has limitations in brain research due to the difficulty of precisely replicating the brain's complex multilayered structure and the lack of a platform that can simultaneously analyze both structure and function. A KAIST research team has successfully developed an integrated platform that can implement brain-like layered neuronal structures using 3D printing technology and precisely measure neuronal activity within them.
A joint research team led by Professors Je-Kyun Park and Yoonkey Nam from the Department of Bio and Brain Engineering at KAIST has developed an integrated platform capable of fabricating high-resolution 3D multilayer neuronal networks using low-viscosity natural hydrogels with mechanical properties similar to brain tissue, and simultaneously analyzing their structural and functional connectivity. The study is published in Biosensors and Bioelectronics.
