When the going gets tough, many microbes go dormant. New research discovered a ubiquitous protein that shuts down a cell’s protein production in a f

Most Life on Earth is Dormant, After Pulling an ‘Emergency Brake’

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2024-06-05 15:00:10

When the going gets tough, many microbes go dormant. New research discovered a ubiquitous protein that shuts down a cell’s protein production in a flash.

Researchers recently reported the discovery of a natural protein, named Balon, that can bring a cell’s production of new proteins to a screeching halt. Balon was found in bacteria that hibernate in Arctic permafrost, but it also seems to be made by many other organisms and may be an overlooked mechanism for dormancy throughout the tree of life.

For most life forms, the ability to shut oneself off is a vital part of staying alive. Harsh conditions like lack of food or cold weather can appear out of nowhere. In these dire straits, rather than keel over and die, many organisms have mastered the art of dormancy. They slow down their activity and metabolism. Then, when better times roll back around, they reanimate.

Sitting around in a dormant state is actually the norm for the majority of life on Earth: By some estimates, 60% of all microbial cells are hibernating at any given time. Even in organisms whose entire bodies do not go dormant, like most mammals, some cellular populations within them rest and wait for the best time to activate.

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