THE RESULTS OF OUR 3-YEAR RANDOMISED CONTROLLED TRIAL IN YOGYAKARTA PROVIDE COMPELLING GOLD STANDARD EVIDENCE FOR THE EFFICACY OF THE WOLBACHIA METHOD IN CONTROLLING DENGUE.
In order to measure the efficacy of the Wolbachia method, WMP, in collaboration with partners the Tahija Foundation and Gadjah Mada University, conducted a Cluster Randomised Controlled Trial within a 26km2 area of Yogyakarta City, Indonesia.
The aim of the study was to determine whether deployment of Wolbachia-carrying Aedes aegypti mosquitoes leads to a reduction in dengue incidence in Wolbachia-treated versus untreated areas. The study site was subdivided into 24 clusters, among which 12 were randomly selected to receive Wolbachia mosquito releases alongside routine dengue control measures alongside routine dengue control measures. The remaining 12 continued to receive routine dengue control measures.
Following the successful establishment of Wolbachia, consenting patients presenting with fever were enrolled at a network of primary care clinics across the study area over a period of 27 months, and were tested for dengue.