Prof Ewan Birney, deputy director general of the European Molecular Biology Laboratory, said: "It will help clinical researchers prioritise where to look to find areas that could cause disease."
All living organisms are built from DNA. It is made from four blocks of chemicals called adenine (A), cytosine (C), guanine (G) and thymine (T). In humans, when an embryo is developing, the order of these letters are read to produce proteins, which are the building blocks of the the cells and tissues that make up various parts of the body.
But if the letters are in the wrong order - perhaps because of an inherited disorder - the body cells and tissues aren't made properly - and this can lead to disease.
The new system, called AlphaMissense, can tell If the letters in the DNA will produce the correct shape. If not, it is listed as potentially disease-causing.
Currently genetic disease hunters have fairly limited limited knowledge of which areas of human DNA can lead to disease. They have classified 0.1% of letter changes, or mutations, as either benign or disease causing.