Ion chromatography (IC) is a critical analytical tool on which environmental, food safety, industrial, pharmaceutical, and biopharmaceutical labs rely

Thermo Fisher Scientific 2021 Global IC Symposium

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2021-09-26 15:00:07

Ion chromatography (IC) is a critical analytical tool on which environmental, food safety, industrial, pharmaceutical, and biopharmaceutical labs rely to provide solutions to some of their most challenging problems. Learn how colleagues and experts are using this powerful separation technique across the IC application spectrum to improve their workflows.

Although each day is convenient for a specific region, you can attend any session on any day and they will be recorded for convenient viewing after the symposium.

Throughout the symposium, you can attend the virtual exhibit and take advantage of opportunities to network with other attendees and with Thermo Fisher Scientific.

The advent of Reagent-Free™ Ion Chromatography (RFIC™) has fundamentally changed the practice of ion chromatography in laboratories worldwide. RFIC systems make it possible to perform a wide range of ion chromatographic separations using only deionized water as the carrier. RFIC systems combine three core technologies: electrolytic eluent generation that generates acid, base, or salt eluents for IC separations, self-regenerating electrolytic suppression that produces the regenerant ions necessary for eluent suppression, and continuously regenerated trap column (CR-TC) that removes trace-level contaminants. For many applications, RFIC systems provide high performance with increased sensitivity and the flexibility to perform isocratic and gradient separations using alkali hydroxides (e.g., KOH), methanesulfonic acid (MSA), or carbonate/bicarbonate eluents. The RFIC systems offer IC users the benefits of simplicity and ease of use, and improved reproducibility. In addition to saving time, labor, and operating costs, RFIC systems eliminate errors associated with manual eluent preparation. This effectively improves IC method performance and reproducibility. In this presentation, we will review the operation principles and development history of key electrolytic devices used in the RFIC systems. We will also discuss the current state-of-the art of RFIC systems and their used in conventional-scale and capillary-scale IC separations of target analytes in various sample matrices.

This presentation will detail the latest capability in high-performance suppressed ion chromatography coupled with mass spectrometry detection, specifically triple-quadrupole mass spectrometry for quantitative applications. Working with colleagues across fields of environmental sciences and climate change, natural product development and the aquacultural sciences, our IC-MS system has delivered outstanding sensitivity and analytical performance in applications where selective trace and ultra-trace analysis of small inorganic and organic ions are required. The presentation will include three specific projects, the analysis of aerosols for bushfire biomarkers, the analysis of aquacultural saline waters for oxyhalides species, and the analysis of xylooligosaccharides from lignocellulosic biomass. Challenges, solutions and quantitative outcomes will be presented.