Mortality is consistently twice as high in transgender people receiving hormone treatment compared with cisgender individuals in the general populatio

Transgender Individuals Twice as Likely to Die Early as General Population

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2022-01-15 03:30:05

Mortality is consistently twice as high in transgender people receiving hormone treatment compared with cisgender individuals in the general population and has not decreased over time, shows a five decades-long study from the Netherlands.

Particularly concerning is that trans women (male to female) had a mortality risk nearly double that of cis men (born and remain male) in the general Dutch population (standardized mortality ratio [SMR], 1.8), while it was nearly triple that of cis women (SMR, 2.8).

Compared with cisgender women, transgender women were more than twice as likely to die from heart disease, three times more likely to die from lung cancer, and almost nine times more likely to die from infection. HIV-related disease mortality risk was nearly 50 times higher for trans women than cis women, and the risk of suicide was almost seven times greater.  

The report, by Christel J.M. de Blok, MD, of Amsterdam University Medical Center, the Netherlands, and colleagues, was published online September 2 in The Lancet Diabetes & Endocrinology.

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