January 24, 2023
by Louise Lerner, University of Chicago
A study by chemists at the University of Chicago has uncovered a new key step in the process that HIV uses to replicate itself.
The study, published Jan. 6 in Science Advances, used computer modeling to focus on how HIV forms a capsule that carries its genetic material—in particular, the role of a particular ion known as IP6. Scientists had previously suspected IP6 has an important function but didn't know exactly how it worked.
The theory may explain aspects of the success of a promising new drug, as well as point the way to other treatments. Replicating replication