Creating the FlyWire Brain Connectome
Since 2019, scientists and experienced proofreaders have utilized FlyWire to proofread AI segmentation of a full fly brain (Dorkenwald et al., Zheng et al.). As of October 2024, the flagship FlyWire paper, Neuronal wiring diagram of an adult brain, has been published in Nature, which includes 139,255 proofread neurons (Dorkenwald et al.). The companion papers include hierarchical annotation of all proofread neurons (Schlegel et al.) and a comprehensive cell type catalog of the visual system (Matsliah, Yu et al.).
Automatically extracted presynaptic and postsynaptic tags have been applied to all putative connections in the brain (Buhmann et al.), and the dominant neurotransmitter assigned for most neurons (Eckstein et al.).
Community of neurobiologists, computer scientists, and proofreaders who build and curate the first whole brain connectome for Drosophila in FlyWire. Join FlyWire and contribute community data for your lab to appear.
