It was August 2017, and pleasant and breezy in the central mountains of Madagascar. The passengers loading their bags into the minibus leaving Ankazobe, a small town in the highlands, were grateful for the morning coolness. It would be warm and sticky on the trip they were taking to Antananarivo, the island’s million-person capital 100 kilometers to the south, and then to Toamasina on the coast, another 350 kilometers away. One of the passengers, a 31-year-old man, looked uncomfortable already. Four days before, he had arrived on a visit. Now he was headed home, but he was feverish, achy, and shaking with chills.
He never made it. The man died in the minibus after it drove through the capital; the panicked driver dropped his body off at a hospital and then continued toward the coast.
Within days, 31 people linked to the taxi trip and the hospital fell ill, and four died. Two weeks later, a woman with no known ties to the trip died in the densely packed capital. Shortly after, doctors discovered what was killing them: plague. By early October, there were 169 cases scattered across the island nation. By the end of the month, there were more than 1,500.